Cargando…
The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements
As a class of essential enzymes in protein translation, aminoacyl–transfer RNA (tRNA) synthetases (aaRSs) are organized into two classes of 10 enzymes each, based on two conserved active site architectures. The (αβ)(2) glycyl-tRNA synthetase (GlyRS) in many bacteria is an orphan aaRS whose sequence...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908026/ https://www.ncbi.nlm.nih.gov/pubmed/36753552 http://dx.doi.org/10.1126/sciadv.adf1027 |