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Combining the External Medical Knowledge Graph Embedding to Improve the Performance of Syndrome Differentiation Model

The electronic medical records (EMRs) of traditional Chinese medicine (TCM) include a wealth of TCM knowledge and syndrome diagnosis information, which is crucial for improving the quality of TCM auxiliary decision-making. In practical diagnosis, one disease corresponds to one syndrome, posing consi...

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Detalles Bibliográficos
Autores principales: Ye, Qing, Yang, Rui, Cheng, Chun-lei, Peng, Lin, Lan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908338/
https://www.ncbi.nlm.nih.gov/pubmed/36777631
http://dx.doi.org/10.1155/2023/2088698
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author Ye, Qing
Yang, Rui
Cheng, Chun-lei
Peng, Lin
Lan, Yong
author_facet Ye, Qing
Yang, Rui
Cheng, Chun-lei
Peng, Lin
Lan, Yong
author_sort Ye, Qing
collection PubMed
description The electronic medical records (EMRs) of traditional Chinese medicine (TCM) include a wealth of TCM knowledge and syndrome diagnosis information, which is crucial for improving the quality of TCM auxiliary decision-making. In practical diagnosis, one disease corresponds to one syndrome, posing considerable hurdles for the informatization of TCM. The purpose of this work was to create an end-to-end TCM diagnostic model, and the knowledge graph (KG) created in this article is used to improve the model's information and realize auxiliary decision-making for TCM disorders. We approached auxiliary decision-making for syndrome differentiation in this article as a multilabel classification task and presented a knowledge-based decision support model for syndrome differentiation (KDSD). Specifically, we created a KG based on TCM features (TCMKG), supplementing the textual representation of medical data with embedded information. Finally, we proposed fusing medical text with KG entity representation (F-MT-KER) to get prediction results using a linear output layer. After obtaining the vector representation of the medical record text using the BERT model, the vector representation of various KG embedded models can provide additional hidden information to a certain extent. Experimental results show that our method improves by 1% (P@1) on the syndrome differentiation auxiliary decision task compared to the baseline model BERT. The usage of EMRs can aid TCM development more efficiently. With the help of entity level representation, character level representation, and model fusion, the multilabel classification method based on the pretraining model and KG can better simulate the TCM syndrome differentiation of the complex cases.
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spelling pubmed-99083382023-02-09 Combining the External Medical Knowledge Graph Embedding to Improve the Performance of Syndrome Differentiation Model Ye, Qing Yang, Rui Cheng, Chun-lei Peng, Lin Lan, Yong Evid Based Complement Alternat Med Research Article The electronic medical records (EMRs) of traditional Chinese medicine (TCM) include a wealth of TCM knowledge and syndrome diagnosis information, which is crucial for improving the quality of TCM auxiliary decision-making. In practical diagnosis, one disease corresponds to one syndrome, posing considerable hurdles for the informatization of TCM. The purpose of this work was to create an end-to-end TCM diagnostic model, and the knowledge graph (KG) created in this article is used to improve the model's information and realize auxiliary decision-making for TCM disorders. We approached auxiliary decision-making for syndrome differentiation in this article as a multilabel classification task and presented a knowledge-based decision support model for syndrome differentiation (KDSD). Specifically, we created a KG based on TCM features (TCMKG), supplementing the textual representation of medical data with embedded information. Finally, we proposed fusing medical text with KG entity representation (F-MT-KER) to get prediction results using a linear output layer. After obtaining the vector representation of the medical record text using the BERT model, the vector representation of various KG embedded models can provide additional hidden information to a certain extent. Experimental results show that our method improves by 1% (P@1) on the syndrome differentiation auxiliary decision task compared to the baseline model BERT. The usage of EMRs can aid TCM development more efficiently. With the help of entity level representation, character level representation, and model fusion, the multilabel classification method based on the pretraining model and KG can better simulate the TCM syndrome differentiation of the complex cases. Hindawi 2023-02-01 /pmc/articles/PMC9908338/ /pubmed/36777631 http://dx.doi.org/10.1155/2023/2088698 Text en Copyright © 2023 Qing Ye et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ye, Qing
Yang, Rui
Cheng, Chun-lei
Peng, Lin
Lan, Yong
Combining the External Medical Knowledge Graph Embedding to Improve the Performance of Syndrome Differentiation Model
title Combining the External Medical Knowledge Graph Embedding to Improve the Performance of Syndrome Differentiation Model
title_full Combining the External Medical Knowledge Graph Embedding to Improve the Performance of Syndrome Differentiation Model
title_fullStr Combining the External Medical Knowledge Graph Embedding to Improve the Performance of Syndrome Differentiation Model
title_full_unstemmed Combining the External Medical Knowledge Graph Embedding to Improve the Performance of Syndrome Differentiation Model
title_short Combining the External Medical Knowledge Graph Embedding to Improve the Performance of Syndrome Differentiation Model
title_sort combining the external medical knowledge graph embedding to improve the performance of syndrome differentiation model
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908338/
https://www.ncbi.nlm.nih.gov/pubmed/36777631
http://dx.doi.org/10.1155/2023/2088698
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