Case report: An autopsy case of pilsicainide poisoning

We present a fatal case of pilsicainide poisoning. Quantitative toxicological analysis revealed that the concentrations of pilsicainide in femoral blood and urine samples were 17.5 μg/mL and 136.9 μg/mL, respectively. No morphological changes due to poisoning were observed. Based on the autopsy find...

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Detalles Bibliográficos
Autores principales: Takei, Sella, Kinoshita, Hiroshi, Kumihashi, Mitsuru, Jamal, Mostofa, Abe, Hiroko, Kimura, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908605/
https://www.ncbi.nlm.nih.gov/pubmed/36778006
http://dx.doi.org/10.3389/fphar.2023.1090265
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author Takei, Sella
Kinoshita, Hiroshi
Kumihashi, Mitsuru
Jamal, Mostofa
Abe, Hiroko
Kimura, Shoji
author_facet Takei, Sella
Kinoshita, Hiroshi
Kumihashi, Mitsuru
Jamal, Mostofa
Abe, Hiroko
Kimura, Shoji
author_sort Takei, Sella
collection PubMed
description We present a fatal case of pilsicainide poisoning. Quantitative toxicological analysis revealed that the concentrations of pilsicainide in femoral blood and urine samples were 17.5 μg/mL and 136.9 μg/mL, respectively. No morphological changes due to poisoning were observed. Based on the autopsy findings, results of the toxicological examination, and investigation by the authorities, we concluded that the cause of death was due to pilsicainide poisoning.
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spelling pubmed-99086052023-02-10 Case report: An autopsy case of pilsicainide poisoning Takei, Sella Kinoshita, Hiroshi Kumihashi, Mitsuru Jamal, Mostofa Abe, Hiroko Kimura, Shoji Front Pharmacol Pharmacology We present a fatal case of pilsicainide poisoning. Quantitative toxicological analysis revealed that the concentrations of pilsicainide in femoral blood and urine samples were 17.5 μg/mL and 136.9 μg/mL, respectively. No morphological changes due to poisoning were observed. Based on the autopsy findings, results of the toxicological examination, and investigation by the authorities, we concluded that the cause of death was due to pilsicainide poisoning. Frontiers Media S.A. 2023-01-26 /pmc/articles/PMC9908605/ /pubmed/36778006 http://dx.doi.org/10.3389/fphar.2023.1090265 Text en Copyright © 2023 Takei, Kinoshita, Kumihashi, Jamal, Abe and Kimura. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Takei, Sella
Kinoshita, Hiroshi
Kumihashi, Mitsuru
Jamal, Mostofa
Abe, Hiroko
Kimura, Shoji
Case report: An autopsy case of pilsicainide poisoning
title Case report: An autopsy case of pilsicainide poisoning
title_full Case report: An autopsy case of pilsicainide poisoning
title_fullStr Case report: An autopsy case of pilsicainide poisoning
title_full_unstemmed Case report: An autopsy case of pilsicainide poisoning
title_short Case report: An autopsy case of pilsicainide poisoning
title_sort case report: an autopsy case of pilsicainide poisoning
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908605/
https://www.ncbi.nlm.nih.gov/pubmed/36778006
http://dx.doi.org/10.3389/fphar.2023.1090265
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