Characterizing metabolic drivers of Clostridioides difficile infection with activity-based hydrazine probes

Many enzymes require post-translational modifications or cofactor machinery for primary function. As these catalytically essential moieties are highly regulated, they act as dual sensors and chemical handles for context-dependent metabolic activity. Clostridioides difficile is a major nosocomial pat...

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Detalles Bibliográficos
Autores principales: Bustin, Katelyn A., Abbas, Arwa, Wang, Xie, Abt, Michael C., Zackular, Joseph P., Matthews, Megan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908766/
https://www.ncbi.nlm.nih.gov/pubmed/36778002
http://dx.doi.org/10.3389/fphar.2023.1074619

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