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Targeting BAP1 with small compound inhibitor for colon cancer treatment

BRCA1-associated protein-1 (BAP1) is a ubiquitin C-terminal hydrolase domain-containing deubiquitinase. The gene encoding BAP1 is mutated in various human cancers, including mesothelioma, uveal melanoma and renal cell carcinoma. BAP1 plays roles in many cancer-related cellular functions, including c...

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Detalles Bibliográficos
Autores principales: Kang, Minhwa, Park, Seul Gi, Lee, Shin-Ai, Kim, Soyi, Lee, Daye, Shirbhate, Mukesh Eknath, Youn, So-Yeon, Kim, Kwan Mook, Cha, Sun-Shin, Kwon, Jongbum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908887/
https://www.ncbi.nlm.nih.gov/pubmed/36754982
http://dx.doi.org/10.1038/s41598-023-29017-w