MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain

Human acetyltransferases MOZ and MORF are implicated in chromosomal translocations associated with aggressive leukemias. Oncogenic translocations involve the far amino terminus of MOZ/MORF, the function of which remains unclear. Here, we identified and characterized two structured winged helix (WH)...

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Detalles Bibliográficos
Autores principales: Becht, Dustin C., Klein, Brianna J., Kanai, Akinori, Jang, Suk Min, Cox, Khan L., Zhou, Bing-Rui, Phanor, Sabrina K., Zhang, Yi, Chen, Ruo-Wen, Ebmeier, Christopher C., Lachance, Catherine, Galloy, Maxime, Fradet-Turcotte, Amelie, Bulyk, Martha L., Bai, Yawen, Poirier, Michael G., Côté, Jacques, Yokoyama, Akihiko, Kutateladze, Tatiana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908889/
https://www.ncbi.nlm.nih.gov/pubmed/36754959
http://dx.doi.org/10.1038/s41467-023-36368-5

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