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Engineering the lymph node environment promotes antigen-specific efficacy in type 1 diabetes and islet transplantation

Antigen-specific tolerance is a key goal of experimental immunotherapies for autoimmune disease and allograft rejection. This outcome could selectively inhibit detrimental inflammatory immune responses without compromising functional protective immunity. A major challenge facing antigen-specific imm...

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Detalles Bibliográficos
Autores principales: Gammon, Joshua M., Carey, Sean T., Saxena, Vikas, Eppler, Haleigh B., Tsai, Shannon J., Paluskievicz, Christina, Xiong, Yanbao, Li, Lushen, Ackun-Farmmer, Marian, Tostanoski, Lisa H., Gosselin, Emily A., Yanes, Alexis A., Zeng, Xiangbin, Oakes, Robert S., Bromberg, Jonathan S., Jewell, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908900/
https://www.ncbi.nlm.nih.gov/pubmed/36755035
http://dx.doi.org/10.1038/s41467-023-36225-5