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Engineering the lymph node environment promotes antigen-specific efficacy in type 1 diabetes and islet transplantation
Antigen-specific tolerance is a key goal of experimental immunotherapies for autoimmune disease and allograft rejection. This outcome could selectively inhibit detrimental inflammatory immune responses without compromising functional protective immunity. A major challenge facing antigen-specific imm...
Autores principales: | Gammon, Joshua M., Carey, Sean T., Saxena, Vikas, Eppler, Haleigh B., Tsai, Shannon J., Paluskievicz, Christina, Xiong, Yanbao, Li, Lushen, Ackun-Farmmer, Marian, Tostanoski, Lisa H., Gosselin, Emily A., Yanes, Alexis A., Zeng, Xiangbin, Oakes, Robert S., Bromberg, Jonathan S., Jewell, Christopher M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908900/ https://www.ncbi.nlm.nih.gov/pubmed/36755035 http://dx.doi.org/10.1038/s41467-023-36225-5 |
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