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Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes

Snakebite envenoming continues to claim many lives across the globe, necessitating the development of improved therapies. To this end, broadly-neutralizing human monoclonal antibodies may possess advantages over current plasma-derived antivenoms by offering superior safety and high neutralization ca...

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Detalles Bibliográficos
Autores principales:	Ledsgaard, Line, Wade, Jack, Jenkins, Timothy P., Boddum, Kim, Oganesyan, Irina, Harrison, Julian A., Villar, Pedro, Leah, Rachael A., Zenobi, Renato, Schoffelen, Sanne, Voldborg, Bjørn, Ljungars, Anne, McCafferty, John, Lomonte, Bruno, Gutiérrez, José M., Laustsen, Andreas H., Karatt-Vellatt, Aneesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908967/ https://www.ncbi.nlm.nih.gov/pubmed/36755049 http://dx.doi.org/10.1038/s41467-023-36393-4

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