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Advances in the intraoperative delineation of malignant glioma margin
Surgery plays a critical role in the treatment of malignant glioma. However, due to the infiltrative growth and brain shift, it is difficult for neurosurgeons to distinguish malignant glioma margins with the naked eye and with preoperative examinations. Therefore, several technologies were developed...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909013/ https://www.ncbi.nlm.nih.gov/pubmed/36776293 http://dx.doi.org/10.3389/fonc.2023.1114450 |
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author | Jiang, Shan Chai, Huihui Tang, Qisheng |
author_facet | Jiang, Shan Chai, Huihui Tang, Qisheng |
author_sort | Jiang, Shan |
collection | PubMed |
description | Surgery plays a critical role in the treatment of malignant glioma. However, due to the infiltrative growth and brain shift, it is difficult for neurosurgeons to distinguish malignant glioma margins with the naked eye and with preoperative examinations. Therefore, several technologies were developed to determine precise tumor margins intraoperatively. Here, we introduced four intraoperative technologies to delineate malignant glioma margin, namely, magnetic resonance imaging, fluorescence-guided surgery, Raman histology, and mass spectrometry. By tracing their detecting principles and developments, we reviewed their advantages and disadvantages respectively and imagined future trends. |
format | Online Article Text |
id | pubmed-9909013 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-99090132023-02-10 Advances in the intraoperative delineation of malignant glioma margin Jiang, Shan Chai, Huihui Tang, Qisheng Front Oncol Oncology Surgery plays a critical role in the treatment of malignant glioma. However, due to the infiltrative growth and brain shift, it is difficult for neurosurgeons to distinguish malignant glioma margins with the naked eye and with preoperative examinations. Therefore, several technologies were developed to determine precise tumor margins intraoperatively. Here, we introduced four intraoperative technologies to delineate malignant glioma margin, namely, magnetic resonance imaging, fluorescence-guided surgery, Raman histology, and mass spectrometry. By tracing their detecting principles and developments, we reviewed their advantages and disadvantages respectively and imagined future trends. Frontiers Media S.A. 2023-01-26 /pmc/articles/PMC9909013/ /pubmed/36776293 http://dx.doi.org/10.3389/fonc.2023.1114450 Text en Copyright © 2023 Jiang, Chai and Tang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Jiang, Shan Chai, Huihui Tang, Qisheng Advances in the intraoperative delineation of malignant glioma margin |
title | Advances in the intraoperative delineation of malignant glioma margin |
title_full | Advances in the intraoperative delineation of malignant glioma margin |
title_fullStr | Advances in the intraoperative delineation of malignant glioma margin |
title_full_unstemmed | Advances in the intraoperative delineation of malignant glioma margin |
title_short | Advances in the intraoperative delineation of malignant glioma margin |
title_sort | advances in the intraoperative delineation of malignant glioma margin |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909013/ https://www.ncbi.nlm.nih.gov/pubmed/36776293 http://dx.doi.org/10.3389/fonc.2023.1114450 |
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