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Advances in the intraoperative delineation of malignant glioma margin

Surgery plays a critical role in the treatment of malignant glioma. However, due to the infiltrative growth and brain shift, it is difficult for neurosurgeons to distinguish malignant glioma margins with the naked eye and with preoperative examinations. Therefore, several technologies were developed...

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Detalles Bibliográficos
Autores principales: Jiang, Shan, Chai, Huihui, Tang, Qisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909013/
https://www.ncbi.nlm.nih.gov/pubmed/36776293
http://dx.doi.org/10.3389/fonc.2023.1114450
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author Jiang, Shan
Chai, Huihui
Tang, Qisheng
author_facet Jiang, Shan
Chai, Huihui
Tang, Qisheng
author_sort Jiang, Shan
collection PubMed
description Surgery plays a critical role in the treatment of malignant glioma. However, due to the infiltrative growth and brain shift, it is difficult for neurosurgeons to distinguish malignant glioma margins with the naked eye and with preoperative examinations. Therefore, several technologies were developed to determine precise tumor margins intraoperatively. Here, we introduced four intraoperative technologies to delineate malignant glioma margin, namely, magnetic resonance imaging, fluorescence-guided surgery, Raman histology, and mass spectrometry. By tracing their detecting principles and developments, we reviewed their advantages and disadvantages respectively and imagined future trends.
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spelling pubmed-99090132023-02-10 Advances in the intraoperative delineation of malignant glioma margin Jiang, Shan Chai, Huihui Tang, Qisheng Front Oncol Oncology Surgery plays a critical role in the treatment of malignant glioma. However, due to the infiltrative growth and brain shift, it is difficult for neurosurgeons to distinguish malignant glioma margins with the naked eye and with preoperative examinations. Therefore, several technologies were developed to determine precise tumor margins intraoperatively. Here, we introduced four intraoperative technologies to delineate malignant glioma margin, namely, magnetic resonance imaging, fluorescence-guided surgery, Raman histology, and mass spectrometry. By tracing their detecting principles and developments, we reviewed their advantages and disadvantages respectively and imagined future trends. Frontiers Media S.A. 2023-01-26 /pmc/articles/PMC9909013/ /pubmed/36776293 http://dx.doi.org/10.3389/fonc.2023.1114450 Text en Copyright © 2023 Jiang, Chai and Tang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Jiang, Shan
Chai, Huihui
Tang, Qisheng
Advances in the intraoperative delineation of malignant glioma margin
title Advances in the intraoperative delineation of malignant glioma margin
title_full Advances in the intraoperative delineation of malignant glioma margin
title_fullStr Advances in the intraoperative delineation of malignant glioma margin
title_full_unstemmed Advances in the intraoperative delineation of malignant glioma margin
title_short Advances in the intraoperative delineation of malignant glioma margin
title_sort advances in the intraoperative delineation of malignant glioma margin
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909013/
https://www.ncbi.nlm.nih.gov/pubmed/36776293
http://dx.doi.org/10.3389/fonc.2023.1114450
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