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T cells and their products in diabetic kidney disease
Diabetic kidney disease (DKD) is the most common cause of end-stage renal disease and has gradually become a public health problem worldwide. DKD is increasingly recognized as a comprehensive inflammatory disease that is largely regulated by T cells. Given the pivotal role of T cells and T cells-pro...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909022/ https://www.ncbi.nlm.nih.gov/pubmed/36776877 http://dx.doi.org/10.3389/fimmu.2023.1084448 |
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author | Liu, Yue Lv, Yaodong Zhang, Tingwei Huang, Tongtong Lang, Yating Sheng, Qinghao Liu, Yingxiao Kong, Zhijuan Gao, Ying Lu, Shangwei Yang, Meilin Luan, Yaqi Wang, Xining Lv, Zhimei |
author_facet | Liu, Yue Lv, Yaodong Zhang, Tingwei Huang, Tongtong Lang, Yating Sheng, Qinghao Liu, Yingxiao Kong, Zhijuan Gao, Ying Lu, Shangwei Yang, Meilin Luan, Yaqi Wang, Xining Lv, Zhimei |
author_sort | Liu, Yue |
collection | PubMed |
description | Diabetic kidney disease (DKD) is the most common cause of end-stage renal disease and has gradually become a public health problem worldwide. DKD is increasingly recognized as a comprehensive inflammatory disease that is largely regulated by T cells. Given the pivotal role of T cells and T cells-producing cytokines in DKD, we summarized recent advances concerning T cells in the progression of type 2 diabetic nephropathy and provided a novel perspective of immune-related factors in diabetes. Specific emphasis is placed on the classification of T cells, process of T cell recruitment, function of T cells in the development of diabetic kidney damage, and potential treatments and therapeutic strategies involving T cells. |
format | Online Article Text |
id | pubmed-9909022 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-99090222023-02-10 T cells and their products in diabetic kidney disease Liu, Yue Lv, Yaodong Zhang, Tingwei Huang, Tongtong Lang, Yating Sheng, Qinghao Liu, Yingxiao Kong, Zhijuan Gao, Ying Lu, Shangwei Yang, Meilin Luan, Yaqi Wang, Xining Lv, Zhimei Front Immunol Immunology Diabetic kidney disease (DKD) is the most common cause of end-stage renal disease and has gradually become a public health problem worldwide. DKD is increasingly recognized as a comprehensive inflammatory disease that is largely regulated by T cells. Given the pivotal role of T cells and T cells-producing cytokines in DKD, we summarized recent advances concerning T cells in the progression of type 2 diabetic nephropathy and provided a novel perspective of immune-related factors in diabetes. Specific emphasis is placed on the classification of T cells, process of T cell recruitment, function of T cells in the development of diabetic kidney damage, and potential treatments and therapeutic strategies involving T cells. Frontiers Media S.A. 2023-01-26 /pmc/articles/PMC9909022/ /pubmed/36776877 http://dx.doi.org/10.3389/fimmu.2023.1084448 Text en Copyright © 2023 Liu, Lv, Zhang, Huang, Lang, Sheng, Liu, Kong, Gao, Lu, Yang, Luan, Wang and Lv https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Liu, Yue Lv, Yaodong Zhang, Tingwei Huang, Tongtong Lang, Yating Sheng, Qinghao Liu, Yingxiao Kong, Zhijuan Gao, Ying Lu, Shangwei Yang, Meilin Luan, Yaqi Wang, Xining Lv, Zhimei T cells and their products in diabetic kidney disease |
title | T cells and their products in diabetic kidney disease |
title_full | T cells and their products in diabetic kidney disease |
title_fullStr | T cells and their products in diabetic kidney disease |
title_full_unstemmed | T cells and their products in diabetic kidney disease |
title_short | T cells and their products in diabetic kidney disease |
title_sort | t cells and their products in diabetic kidney disease |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909022/ https://www.ncbi.nlm.nih.gov/pubmed/36776877 http://dx.doi.org/10.3389/fimmu.2023.1084448 |
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