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Microtubule stabilization promotes the synthesis of type 2 collagen in nucleus pulposus cell by activating hippo-yap pathway

Intervertebral disc degeneration (IDD) is the cardinal pathological mechanism that underlies low back pain. Mechanical stress of the intervertebral disc may result in a change in nucleus pulposus cells state, matrix degradation, and degeneration of the disc. Microtubules, which are components of the...

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Detalles Bibliográficos
Autores principales:	Zhang, Xin, Shu, Shibin, Feng, Zhenhua, Qiu, Yong, Bao, Hongda, Zhu, Zezhang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909034/ https://www.ncbi.nlm.nih.gov/pubmed/36778003 http://dx.doi.org/10.3389/fphar.2023.1102318

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