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In critically ill patients, anti-anaerobic antibiotics increase risk of adverse clinical outcomes
BACKGROUND: Critically ill patients routinely receive antibiotics with activity against anaerobic gut bacteria. However, in other disease states and animal models, gut anaerobes are protective against pneumonia, organ failure and mortality. We therefore designed a translational series of analyses an...
Autores principales: | Chanderraj, Rishi, Baker, Jennifer M., Kay, Stephen G., Brown, Christopher A., Hinkle, Kevin J., Fergle, Daniel J., McDonald, Roderick A., Falkowski, Nicole R., Metcalf, Joseph D., Kaye, Keith S., Woods, Robert J., Prescott, Hallie C., Sjoding, Michael W., Dickson, Robert P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909213/ https://www.ncbi.nlm.nih.gov/pubmed/36229047 http://dx.doi.org/10.1183/13993003.00910-2022 |
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