The residues 4 to 6 at the N-terminus in particular modulate fibril propagation of β (2)-microglobulin : N-terminal modulates β2M fibril propagation

The ΔN6 truncation is the main posttranslational modification of β (2)-microglobulin (β (2)M) found in dialysis-related amyloid. Investigation of the interaction of wild-type (WT) β (2)M with N-terminally truncated variants is therefore of medical relevance. However, it is unclear which residues amo...

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Detalles Bibliográficos
Autores principales: Dang, Haibin, Chen, Zhixian, Chen, Wang, Luo, Xudong, Liu, Pan, Wang, Liqiang, Chen, Jie, Tang, Xuhai, Wang, Zhengzhi, Liang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909321/
https://www.ncbi.nlm.nih.gov/pubmed/35130623
http://dx.doi.org/10.3724/abbs.2021017

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