Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages

INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) has a global prevalence of 25% of the population and is a leading cause of cirrhosis and hepatocellular carcinoma. NAFLD ranges from simple steatosis (non-alcoholic fatty liver) to non-alcoholic steatohepatitis (NASH). Hepatic macrophages, spec...

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Detalles Bibliográficos
Autores principales: Drummer, Charles, Saaoud, Fatma, Jhala, Nirag C., Cueto, Ramon, Sun, Yu, Xu, Keman, Shao, Ying, Lu, Yifan, Shen, Huimin, Yang, Ling, Zhou, Yan, Yu, Jun, Wu, Sheng, Snyder, Nathaniel W., Hu, Wenhui, Zhuo, Jia ‘Joe’, Zhong, Yinghui, Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909353/
https://www.ncbi.nlm.nih.gov/pubmed/36776889
http://dx.doi.org/10.3389/fimmu.2023.1113883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909353/
https://www.ncbi.nlm.nih.gov/pubmed/36776889
http://dx.doi.org/10.3389/fimmu.2023.1113883

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