Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior

Brain and muscle ARNT-like 1 (BMAL1) is a core circadian clock protein and transcription factor that regulates many physiological functions, including blood pressure (BP). Male global Bmal1 knockout (KO) mice exhibit ∼10 mmHg reduction in BP, as well as a blunting of BP rhythm. The mechanisms of how...

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Detalles Bibliográficos
Autores principales: Costello, Hannah M, Crislip, G Ryan, Cheng, Kit-Yan, Lynch, I Jeanette, Juffre, Alexandria, Bratanatawira, Phillip, Mckee, Annalisse, Thelwell, Ryanne S, Mendez, Victor M, Wingo, Charles S, Douma, Lauren G, Gumz, Michelle L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909366/
https://www.ncbi.nlm.nih.gov/pubmed/36778748
http://dx.doi.org/10.1093/function/zqad001

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