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Comparing Transgenic Production to Supplementation of ω-3 PUFA Reveals Distinct But Overlapping Mechanisms Underlying Protection Against Metabolic and Hepatic Disorders

We compared endogenous ω-3 PUFA production to supplementation for improving obesity-related metabolic dysfunction. Fat-1 transgenic mice, who endogenously convert exogenous ω-6 to ω-3 PUFA, and wild-type littermates were fed a high-fat diet and a daily dose of either ω-3 or ω-6 PUFA-rich oil for 12...

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Detalles Bibliográficos
Autores principales:	Daniel, Noëmie, Le Barz, Mélanie, Mitchell, Patricia L, Varin, Thibault V, Julien, Isabelle Bourdeau, Farabos, Dominique, Pilon, Geneviève, Gauthier, Josée, Garofalo, Carole, Kang, Jing X, Trottier, Jocelyn, Barbier, Olivier, Roy, Denis, Chassaing, Benoit, Levy, Emile, Raymond, Frédéric, Lamaziere, Antonin, Flamand, Nicolas, Silvestri, Cristoforo, Jobin, Christian, Di Marzo, Vincenzo, Marette, André
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909367/ https://www.ncbi.nlm.nih.gov/pubmed/36778746 http://dx.doi.org/10.1093/function/zqac069

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