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In-Vial Detection of Protein Denaturation Using Intrinsic Fluorescence Anisotropy

[Image: see text] The conventional quality control techniques for identifying the denaturation of biopharmaceuticals includes sodium dodecyl sulfate-polyacrylamide gel electrophoresis for identifying fragmentation, ion exchange chromatography and isoelectric focusing for identifying deamidation, rev...

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Detalles Bibliográficos
Autores principales: Chullipalliyalil, Krishnakumar, Elkassas, Khaled, McAuliffe, Michael A. P., Vucen, Sonja, Crean, Abina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909669/
https://www.ncbi.nlm.nih.gov/pubmed/36696963
http://dx.doi.org/10.1021/acs.analchem.2c03912

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