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In-Vial Detection of Protein Denaturation Using Intrinsic Fluorescence Anisotropy
[Image: see text] The conventional quality control techniques for identifying the denaturation of biopharmaceuticals includes sodium dodecyl sulfate-polyacrylamide gel electrophoresis for identifying fragmentation, ion exchange chromatography and isoelectric focusing for identifying deamidation, rev...
Autores principales: | Chullipalliyalil, Krishnakumar, Elkassas, Khaled, McAuliffe, Michael A. P., Vucen, Sonja, Crean, Abina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909669/ https://www.ncbi.nlm.nih.gov/pubmed/36696963 http://dx.doi.org/10.1021/acs.analchem.2c03912 |
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