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Combined Cancer Immunotheranostic Nanomedicines: Delivery Technologies and Therapeutic Outcomes

[Image: see text] Cancer is among the main causes of mortality all over the world. The delayed diagnosis is directly related to the decrease in survival rate. The use of immunotherapy has dramatically changed the treatment outcomes of different types of cancers. However, many patients still do not r...

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Detalles Bibliográficos
Autores principales: Nasser, Tasneem A., Adel, Rawan, Badr, Abdelrahman, Teleb, Mohamed, Bekhit, Adnan A., Elkhodairy, Kadria A., Abdelhamid, Ahmed S., Elzoghby, Ahmed O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909687/
https://www.ncbi.nlm.nih.gov/pubmed/36777563
http://dx.doi.org/10.1021/acsomega.2c05986
Descripción
Sumario:[Image: see text] Cancer is among the main causes of mortality all over the world. The delayed diagnosis is directly related to the decrease in survival rate. The use of immunotherapy has dramatically changed the treatment outcomes of different types of cancers. However, many patients still do not respond to immunotherapies, and many also suffer from severe immune-related side effects. Recent advances in the fields of nanomedicine bioengineering and in particular imaging offered new approaches which can enhance not only the safety but also the efficacy of immunotherapy. Theranostics has showed great progress as a branch of medicine which integrates both diagnosis and therapy in a single system. The outcomes from animal studies demonstrated an improvement in the diagnostic and immunotherapeutic potential of nanoparticles within the theranostic framework. Herein, we discuss the most recent developments in the application of nanotheranostics for combining tumor imaging and cancer immunotherapies.