Cargando…

Synthesis and biological evaluation of coumarin-quinone hybrids as multifunctional bioactive agents

We report the synthesis, structural characterization and pharmaceutical activity of four coumarin-quinone hybrids. The compounds were significantly active against Staphylococcus aureus, Pseudomonas aeoginosa and Candida albicans. Promising antioxidant activity was observed when compared to ascorbic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pangal, Anees, Ahmed, Khursheed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Association of Physical Chemists 2022
Materias:	Original Scientific Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909729/ https://www.ncbi.nlm.nih.gov/pubmed/36778907 http://dx.doi.org/10.5599/admet.1468

Ejemplares similares

The Synthesis and Biological Evaluation of Aloe-Emodin-Coumarin Hybrids as Potential Antitumor Agents
por: Shang, Hai, et al.
Publicado: (2022)

Synthesis and Biological Evaluation of Harmirins, Novel Harmine–Coumarin Hybrids as Potential Anticancer Agents
por: Pavić, Kristina, et al.
Publicado: (2021)

Design, Synthesis and Bioactivity Evaluation of Coumarin–BMT Hybrids as New Acetylcholinesterase Inhibitors
por: Zeng, Fanxin, et al.
Publicado: (2022)

Design, synthesis, and evaluation of 3,7-substituted coumarin derivatives as multifunctional Alzheimer’s disease agents
por: Mzezewa, Sheunopa C., et al.
Publicado: (2021)

Synthesis and Biological Evaluation of Piperazine Hybridized Coumarin Indolylcyanoenones with Antibacterial Potential
por: Zeng, Chunmei, et al.
Publicado: (2023)

Novel coumarin-6-sulfonamides as apoptotic anti-proliferative agents: synthesis, in vitro biological evaluation, and QSAR studies
por: Sabt, Ahmed, et al.
Publicado: (2018)

Design, synthesis, in vitro, and in silico biological evaluations of coumarin-indole hybrids as new anti-α-glucosidase agents
por: Niri, Davood Rezapour, et al.
Publicado: (2022)

Synthesis and biological evaluation of 3–(4-aminophenyl)-coumarin derivatives as potential anti-Alzheimer’s disease agents
por: Hu, Yu-Heng, et al.
Publicado: (2019)

Design, Synthesis and Biological Evaluation of Novel 4-Substituted Coumarin Derivatives as Antitumor Agents
por: An, Ran, et al.
Publicado: (2018)

Design, Synthesis and Preliminary Biological Evaluation of Benzylsulfone Coumarin Derivatives as Anti-Cancer Agents
por: Wang, Tao, et al.
Publicado: (2019)

Design, Synthesis, and Mechanism of Dihydroartemisinin–Coumarin Hybrids as Potential Anti-Neuroinflammatory Agents
por: Yu, Haonan, et al.
Publicado: (2019)

Synthesis and Biological Evaluation of Novel Hybrid Molecules Containing Purine, Coumarin and Isoxazoline or Isoxazole Moieties
por: Kallitsakis, Michael G., et al.
Publicado: (2017)

Synthesis and Biological Evaluation of Some New Coumarin Derivatives
por: Al-Haiza, M.A., et al.
Publicado: (2003)

Twenty-first Paterson symposium: bioactivation of quinone anti-tumor agents.
Publicado: (1987)

Design, synthesis, and evaluation of novel coumarin-dithiocarbamate derivatives (IDs) as anti-colorectal cancer agents
por: Zhu, Heping, et al.
Publicado: (2021)

Novel Coumarin 7-Carboxamide/Sulfonamide Derivatives as Potential Fungicidal Agents: Design, Synthesis, and Biological Evaluation
por: Zhang, Shu-Guang, et al.
Publicado: (2022)

Biological synthesis of coumarins in Escherichia coli
por: Yang, So-Mi, et al.
Publicado: (2015)

The plant coumarins auraptene and lacinartin as potential multifunctional therapeutic agents for treating periodontal disease
por: Marquis, Annie, et al.
Publicado: (2012)

Synthesis, characterization and biological investigations of potentially bioactive heterocyclic compounds containing 4-hydroxy coumarin
por: Nagaraja, O., et al.
Publicado: (2020)

Synthesis and Evaluation of New Coumarin Derivatives as Antioxidant, Antimicrobial, and Anti-Inflammatory Agents
por: Alshibl, Hanan M., et al.
Publicado: (2020)

Synthesis and Biological Activity Evaluation of Coumarin-3-Carboxamide Derivatives
por: Phutdhawong, Weerachai, et al.
Publicado: (2021)

Synthesis and Study of Multifunctional Cyclodextrin–Deferasirox Hybrids
por: Gascon, Jose Miguel, et al.
Publicado: (2019)

Quinones as Neuroprotective Agents
por: Cores, Ángel, et al.
Publicado: (2023)

Natural product-inspired synthesis of coumarin–chalcone hybrids as potential anti-breast cancer agents
por: Alhakamy, Nabil A., et al.
Publicado: (2023)

Biological Activity of Coumarin Derivatives as Anti-Leishmanial Agents
por: Mandlik, Vineetha, et al.
Publicado: (2016)

Curcumin–Coumarin Hybrid Analogues as Multitarget Agents in Neurodegenerative Disorders
por: Quezada, Elías, et al.
Publicado: (2021)

Synthesis and Biological Activity of Triterpene–Coumarin Conjugates
por: Vega-Granados, Karina, et al.
Publicado: (2021)

Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents
por: Bruna-Haupt, Ezequiel F., et al.
Publicado: (2023)

Design, synthesis and antiproliferative screening of newly synthesized coumarin-acrylamide hybrids as potential cytotoxic and apoptosis inducing agents
por: Abd El-Lateef, Hany M., et al.
Publicado: (2023)

Synthesis, Bioactivity, Pharmacokinetic and Biomimetic Properties of Multi-Substituted Coumarin Derivatives
por: Katopodi, Annita, et al.
Publicado: (2021)

Three-Component Synthesis of Some New Coumarin Derivatives as Anticancer Agents
por: Alshabanah, Latifah A., et al.
Publicado: (2022)

Design, Synthesis, and Antiproliferative Evaluation of Novel Coumarin/2-Cyanoacryloyl Hybrids as Apoptosis Inducing Agents by Activation of Caspase-Dependent Pathway
por: Zhang, Yu-Ying, et al.
Publicado: (2018)

Bioactivity Profiles of Cytoprotective Short-Chain Quinones
por: Feng, Zikai, et al.
Publicado: (2021)

Halogenated Coumarin–Chalcones as Multifunctional Monoamine Oxidase-B and Butyrylcholinesterase Inhibitors
por: Rehuman, Nisha Abdul, et al.
Publicado: (2021)

Synthesis and Biological Evaluation of Coumarin Triazoles as Dual Inhibitors of Cholinesterases and β-Secretase
por: Sharma, Ankita, et al.
Publicado: (2023)

Recent Advances in Biologically Active Coumarins from Marine Sources: Synthesis and Evaluation
por: Fernández-Peña, Laura, et al.
Publicado: (2022)

Design and Synthesis of Novel Isoxazole Tethered Quinone-Amino Acid Hybrids
por: Ravi Kumar, P., et al.
Publicado: (2014)

An Update on Synthesis of Coumarin Sulfonamides as Enzyme Inhibitors and Anticancer Agents
por: Rubab, Laila, et al.
Publicado: (2022)

Synthesis and biological evaluation of new 3-substituted coumarin derivatives as selective inhibitors of human carbonic anhydrase IX and XII
por: Mahammad Ghouse, Shaik, et al.
Publicado: (2023)

Design and synthesis of coumarin-triazole hybrids: biocompatible anti-diabetic agents, in silico molecular docking and ADME screening
por: Channa Basappa, Vagish, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oc60381efavh5m4emsi6de61gd