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Screening Multidrug Resistance Reversal Agents in Traditional Chinese Medicines by Efflux Kinetics of D-Luciferin in MCF-7/DOX(Fluc) Cells

[Image: see text] In this study, we established a simple and rapid in vitro method for screening multidrug resistance (MDR) reversal agents in traditional Chinese medicines (TCMs), which could better correspond to the MDR reversing effect in vivo. Here, D-luciferin, a substrate for the enzyme firefl...

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Detalles Bibliográficos
Autores principales: Zhao, Yue, Tang, Chaoyuan, Huang, Jingyi, Zhang, Hongyan, Shi, Jingbin, Xu, Shujun, Ma, Lisha, Peng, Chun, Liu, Qi, Xiong, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909823/
https://www.ncbi.nlm.nih.gov/pubmed/36777569
http://dx.doi.org/10.1021/acsomega.2c07096