Cargando…

Mutagenesis of the di-leucine motif in the cytoplasmic tail of newcastle disease virus fusion protein modulates the viral fusion ability and pathogenesis

BACKGROUND: Newcastle disease virus (NDV) is a highly infectious viral disease, which can affect chickens and many other kinds of birds. The main virulence factor of NDV, the fusion (F) protein, is located on the viral envelope and plays a major role in the virus’ ability to penetrate cells and caus...

Descripción completa

Detalles Bibliográficos
Autores principales:	Teng, Qingyuan, Tang, Lihua, Huang, Yahui, Yang, Ruihua, He, Yizhuo, Zhang, Guozhong, Zhao, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909845/ https://www.ncbi.nlm.nih.gov/pubmed/36759854 http://dx.doi.org/10.1186/s12985-023-01985-5

Ejemplares similares

Adaptor complex-mediated trafficking of Newcastle disease virus fusion protein is regulated by the YLMY motif of its cytoplasmic tail
por: Bu, Yawen, et al.
Publicado: (2022)

Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity
por: Bhakta, Sushma J, et al.
Publicado: (2011)

YLMY Tyrosine Residue within the Cytoplasmic Tail of Newcastle Disease Virus Fusion Protein Regulates Its Surface Expression to Modulate Viral Budding and Pathogenicity
por: Bu, Yawen, et al.
Publicado: (2021)

Chimeric rabies glycoprotein with a transmembrane domain and cytoplasmic tail from Newcastle disease virus fusion protein incorporates into the Newcastle disease virion at reduced levels
por: Yu, Gui Mei, et al.
Publicado: (2017)

Antigenic and immunogenic investigation of the virulence motif of the Newcastle disease virus fusion protein
por: Choi, Kang-Seuk, et al.
Publicado: (2010)

Mutation of the TYTLE Motif in the Cytoplasmic Tail of the Sendai Virus Fusion Protein Deeply Affects Viral Assembly and Particle Production
por: Essaidi-Laziosi, Manel, et al.
Publicado: (2013)

Critical Role of the Fusion Protein Cytoplasmic Tail Sequence in Parainfluenza Virus Assembly
por: Stone, Raychel, et al.
Publicado: (2013)

Nipah virus fusion protein: Importance of the cytoplasmic tail for endosomal trafficking and bioactivity
por: Weis, Michael, et al.
Publicado: (2015)

Two Di-Leucine Motifs Regulate Trafficking of Mucolipin-1 to Lysosomes
por: Vergarajauregui, Silvia, et al.
Publicado: (2006)

Syntaxin 8 has two functionally distinct di-leucine-based motifs
por: Kasai, Kazuo, et al.
Publicado: (2007)

Membrane Fusion and Cell Entry of XMRV Are pH-Independent and Modulated by the Envelope Glycoprotein's Cytoplasmic Tail
por: Côté, Marceline, et al.
Publicado: (2012)

Two di-leucine motifs regulate trafficking and function of mouse ASIC2a
por: Wu, Junjun, et al.
Publicado: (2016)

Two mutations in the HR2 region of Newcastle disease virus fusion protein with a cleavage motif “RRQRRL” are critical for fusogenic activity
por: Wang, Yanhong, et al.
Publicado: (2017)

Nanobody-horseradish peroxidase fusion protein as an ultrasensitive probe to detect antibodies against Newcastle disease virus in the immunoassay
por: Sheng, Yamin, et al.
Publicado: (2019)

Different Regions of the Newcastle Disease Virus Fusion Protein Modulate Pathogenicity
por: Heiden, Sandra, et al.
Publicado: (2014)

Role of fusion protein cleavage site in the virulence of Newcastle disease virus
por: Panda, Aruna, et al.
Publicado: (2004)

Modulation of Epstein-Barr Virus Glycoprotein B (gB) Fusion Activity by the gB Cytoplasmic Tail Domain
por: Garcia, Nicholas J., et al.
Publicado: (2013)

Construction and characterization of a novel glucose dehydrogenase-leucine dehydrogenase fusion enzyme for the biosynthesis of l-tert-leucine
por: Liao, Langxing, et al.
Publicado: (2021)

Design and Characterization of Viral Polypeptide Inhibitors Targeting Newcastle Disease Virus Fusion
por: Zhu, Jieqing, et al.
Publicado: (2005)

Strength and Compressive Ability of Midfoot Fusion Nail vs Midfoot Fusion Bolt and Role of Subtalar Fusion
por: Anciano, Victor, et al.
Publicado: (2022)

Mutations in the Methyltransferase Motifs of L Protein Attenuate Newcastle Disease Virus by Regulating Viral Translation and Cell-to-Cell Spread
por: Li, Xiao, et al.
Publicado: (2021)

Integrin Cytoplasmic Tail Interactions
por: Morse, Elizabeth M., et al.
Publicado: (2014)

Species Based Synonymous Codon Usage in Fusion Protein Gene of Newcastle Disease Virus
por: Kumar, Chandra Shekhar, et al.
Publicado: (2014)

The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane
Publicado: (1996)

Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo
Publicado: (1995)

Fusion anomaly of the pancreatic tail and spleen: a case report
por: Omeri, Ahmad Khalid, et al.
Publicado: (2017)

Mutagenesis of the fusion peptide-like domain of hepatitis C virus E1 glycoprotein: involvement in cell fusion and virus entry
por: Li, Hsiao-Fen, et al.
Publicado: (2009)

Studies on the mechanism of membrane fusion: site-specific mutagenesis of the hemagglutinin of influenza virus
Publicado: (1986)

Newcastle Disease Virus Fusion Protein Is the Major Contributor to Protective Immunity of Genotype-Matched Vaccine
por: Kim, Shin-Hee, et al.
Publicado: (2013)

Newcastle disease virus fusion and haemagglutinin-neuraminidase proteins contribute to its macrophage host range
por: Cornax, Ingrid, et al.
Publicado: (2013)

Evaluation of fusion protein cleavage site sequences of Newcastle disease virus in genotype matched vaccines
por: Kim, Shin-Hee, et al.
Publicado: (2017)

Improved immunogenicity of Newcastle disease virus inactivated vaccine following DNA vaccination using Newcastle disease virus hemagglutinin-neuraminidase and fusion protein genes
por: Firouzamandi, Masoumeh, et al.
Publicado: (2016)

A Critical Phenylalanine Residue in the Respiratory Syncytial Virus Fusion Protein Cytoplasmic Tail Mediates Assembly of Internal Viral Proteins into Viral Filaments and Particles
por: Shaikh, Fyza Y., et al.
Publicado: (2012)

C-Terminal Di-leucine Motif of Dopamine D(1) Receptor Plays an Important Role in Its Plasma Membrane Trafficking
por: Guo, Yan, et al.
Publicado: (2011)

Reversible Chemoenzymatic Labeling of Native and Fusion Carrier Protein Motifs
por: Kosa, Nicolas M., et al.
Publicado: (2012)

Sequence motifs and prokaryotic expression of the reptilian paramyxovirus fusion protein
por: Franke, J., et al.
Publicado: (2005)

Genotype-matched Newcastle disease virus vaccine confers improved protection against genotype XII challenge: The importance of cytoplasmic tails in viral replication and vaccine design
por: Izquierdo-Lara, Ray, et al.
Publicado: (2019)

Hybrid- and complex-type N-glycans are not essential for Newcastle disease virus infection and fusion of host cells
por: Sun, Qing, et al.
Publicado: (2012)

Retraction: Newcastle disease virus fusion protein is the major contributor to protective immunity of genotype-matched vaccine
Publicado: (2020)

Acidic Di-leucine Motif Essential for AP-3–dependent Sorting and Restriction of the Functional Specificity of the Vam3p Vacuolar t-SNARE
por: Darsow, Tamara, et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_qrsept8oshblkd2ea03h21ehqe