Triple-tyrosine kinase inhibition by BIBF1000 attenuates airway and pulmonary arterial remodeling following chronic allergen challenges in mice

BACKGROUND: Airway remodeling is an important pathological feature of chronic airway diseases, which leads to a progressive decline in lung function. The present study examined the anti-remodeling and anti- inflammatory effect of BIBF1000, a triple-tyrosine kinase inhibitor that targets VEGF, PDGF,...

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Detalles Bibliográficos
Autores principales: Gurusamy, Malarvizhi, Nasseri, Saeed, Rampa, Dileep Reddy, Feng, Huiying, Lee, Dongwon, Pekcec, Anton, Doods, Henri, Wu, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909896/
https://www.ncbi.nlm.nih.gov/pubmed/36755351
http://dx.doi.org/10.1186/s40001-023-01037-2

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