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SHP-2-induced M2 polarization of tumor associated macrophages via IL-4 regulate colorectal cancer progression
OBJECTIVE: To explore the effect and molecular mechanism of Src homology region 2 domain-containing protein tyrosine phosphatase-2 (SHP-2) in tumor-associated macrophages (TAMs) repressing the migration and invasion of colorectal cancer (CRC) cells. METHODS: The relevant data sets of human colon spe...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909964/ https://www.ncbi.nlm.nih.gov/pubmed/36776333 http://dx.doi.org/10.3389/fonc.2023.1027575 |