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SHP-2-induced M2 polarization of tumor associated macrophages via IL-4 regulate colorectal cancer progression

OBJECTIVE: To explore the effect and molecular mechanism of Src homology region 2 domain-containing protein tyrosine phosphatase-2 (SHP-2) in tumor-associated macrophages (TAMs) repressing the migration and invasion of colorectal cancer (CRC) cells. METHODS: The relevant data sets of human colon spe...

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Detalles Bibliográficos
Autores principales:	Li, Zhihan, Xi, Jinchuan, Li, Baokun, Liu, Youqiang, Wang, Guiying, Yu, Bin, Ma, Hongqing, Li, Zhilin, Zhang, Zhenya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909964/ https://www.ncbi.nlm.nih.gov/pubmed/36776333 http://dx.doi.org/10.3389/fonc.2023.1027575

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