Procoxacin bidirectionally inhibits osteoblastic and osteoclastic activity in bone and suppresses bone metastasis of prostate cancer

BACKGROUND: Bone is the most common site of metastasis of prostate cancer (PCa). PCa invasion leads to a disruption of osteogenic-osteolytic balance and causes abnormal bone formation. The interaction between PCa and bone stromal cells, especially osteoblasts (OB), is considered essential for the di...

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Detalles Bibliográficos
Autores principales: Kong, Depei, Ye, Chen, Zhang, Chenxi, Sun, Xiaochen, Wang, Fubo, Chen, Rui, Xiao, Guangan, He, Shipeng, Xu, Jianrong, Rao, Xiwu, Ai, Jianzhong, Gao, Xu, Li, Hong, Su, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909988/
https://www.ncbi.nlm.nih.gov/pubmed/36759880
http://dx.doi.org/10.1186/s13046-023-02610-7

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