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Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation

Xanthine dehydrogenase (XDH) is the rate-limiting enzyme in purine catabolism by converting hypoxanthine to xanthine and xanthine to uric acid. The altered expression and activity of XDH are associated with the development and prognosis of multiple types of cancer, while its role in lung adenocarcin...

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Detalles Bibliográficos
Autores principales:	Chen, Man-man, Guo, Wei, Chen, Si-meng, Guo, Xiao-zhen, Xu, Lan, Ma, Xiao-yu, Wang, Yu-xiang, Xie, Cen, Meng, Ling-hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909990/ https://www.ncbi.nlm.nih.gov/pubmed/36778128 http://dx.doi.org/10.7150/ijbs.78948

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