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Regulating Neutrophil PAD4/NOX-Dependent Cerebrovasular Thromboinflammation

Background: Neutrophil extracellular trap (NET) production has been implicated in the pathogenesis of thromboinflammatory conditions such as Sickle Cell Disease (SCD), contributing to heightened risk for ischemic stroke. NETs are catalyzed by the enzyme Peptidyl Arginine Deiminase 4 (PAD4) and neutr...

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Detalles Bibliográficos
Autores principales: Ansari, Junaid, Vital, Shantel A., Yadav, Shreya, Gavins, Felicity N. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910005/
https://www.ncbi.nlm.nih.gov/pubmed/36778112
http://dx.doi.org/10.7150/ijbs.77434

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