Ubiquitin like protein FAT10 repressed cardiac fibrosis after myocardial ischemic via mediating degradation of Smad3 dependent on FAT10-proteasome system

Cardiac fibrosis after myocardial ischemic (MI) injury is a key factor in heart function deterioration. We recently showed that ubiquitin-like protein human HLA-F adjacent transcript (FAT10) plays a novel role in ischemic cardiovascular diseases, but its function in cardiac fibrosis remains unknown....

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Detalles Bibliográficos
Autores principales: Chen, Chen, Li, Xiaoqing, Zhou, Tao, Su, Yuhao, Yu, Bodong, Jin, Jiejing, Xie, Jinyan, Shen, Yang, Wan, Rong, Hong, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910007/
https://www.ncbi.nlm.nih.gov/pubmed/36778114
http://dx.doi.org/10.7150/ijbs.77677

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