Molecular Glues: The Adhesive Connecting Targeted Protein Degradation to the Clinic

[Image: see text] Targeted protein degradation is a rapidly exploding drug discovery strategy that uses small molecules to recruit disease-causing proteins for rapid destruction mainly via the ubiquitin–proteasome pathway. It shows great potential for treating diseases such as cancer and infectious,...

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Detalles Bibliográficos
Autores principales: Sasso, Janet M., Tenchov, Rumiana, Wang, DaSheng, Johnson, Linda S., Wang, Xinmei, Zhou, Qiongqiong Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910052/
https://www.ncbi.nlm.nih.gov/pubmed/35856839
http://dx.doi.org/10.1021/acs.biochem.2c00245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910052/
https://www.ncbi.nlm.nih.gov/pubmed/35856839
http://dx.doi.org/10.1021/acs.biochem.2c00245

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