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Molecular Glues: The Adhesive Connecting Targeted Protein Degradation to the Clinic
[Image: see text] Targeted protein degradation is a rapidly exploding drug discovery strategy that uses small molecules to recruit disease-causing proteins for rapid destruction mainly via the ubiquitin–proteasome pathway. It shows great potential for treating diseases such as cancer and infectious,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910052/ https://www.ncbi.nlm.nih.gov/pubmed/35856839 http://dx.doi.org/10.1021/acs.biochem.2c00245 |