Human alveolar macrophage metabolism is compromised during Mycobacterium tuberculosis infection

Pulmonary macrophages have two distinct ontogenies: long-lived embryonically-seeded alveolar macrophages (AM) and bone marrow-derived macrophages (BMDM). Here, we show that after infection with a virulent strain of Mycobacterium tuberculosis (H37Rv), primary murine AM exhibit a unique transcriptomic...

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Detalles Bibliográficos
Autores principales: Mendonca, Laura E., Pernet, Erwan, Khan, Nargis, Sanz, Joaquin, Kaufmann, Eva, Downey, Jeffrey, Grant, Alexandre, Orlova, Marianna, Schurr, Erwin, Krawczyk, Connie, Jones, Russell G., Barreiro, Luis B., Divangahi, Maziar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910175/
https://www.ncbi.nlm.nih.gov/pubmed/36776396
http://dx.doi.org/10.3389/fimmu.2022.1044592

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