ApoE4 associated with severe COVID-19 outcomes via downregulation of ACE2 and imbalanced RAS pathway

BACKGROUND: Recent numerous epidemiology and clinical association studies reported that ApoE polymorphism might be associated with the risk and severity of coronavirus disease 2019 (COVID-19), and yielded inconsistent results. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection re...

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Detalles Bibliográficos
Autores principales: Chen, Feng, Chen, Yanting, Ke, Qiongwei, Wang, Yongxiang, Gong, Zheng, Chen, Xiongjin, Cai, Yujie, Li, Shengnan, Sun, Yuanhong, Peng, Xiaoping, Ji, Yao, Zhang, Tianzhen, Wu, Wenxian, Cui, Lili, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910247/
https://www.ncbi.nlm.nih.gov/pubmed/36759834
http://dx.doi.org/10.1186/s12967-023-03945-7

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