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Acute promyelocytic leukemia with FIP1L1::RARA fusion gene: The clinical utility of transcriptome sequencing and bioinformatic analyses

BACKGROUND: Acute promyelocytic leukemia (APL) is typically characterized by the presence of coagulopathy and the PML::RARA fusion gene. The FIP1L1::RARA has been reported as a novel fusion gene, but studies on its pathogenesis are limited. OBJECTIVES: A FIP1L1::RARA fusion in a child finally diagno...

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Detalles Bibliográficos
Autores principales: Liu, Guanghua, Long, Jiangwen, Chen, Yuyu, Li, Lingqian, Huan, Xisha, Long, Panpan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910307/
https://www.ncbi.nlm.nih.gov/pubmed/36776354
http://dx.doi.org/10.3389/fonc.2022.1049473