Cargando…

RAGE contributes to allergen driven severe neutrophilic airway inflammation via NLRP3 inflammasome activation in mice

BACKGROUND: Asthma is a major public healthcare burden, affecting over 300 million people worldwide. While there has been great progress in the treatment of asthma, subsets of patients who present with airway neutrophilia, often have more severe disease, and tend to be resistant to conventional cort...

Descripción completa

Detalles Bibliográficos
Autores principales: Killian, Katherine N., Kosanovich, Jessica L., Lipp, Madeline A., Empey, Kerry M., Oury, Tim D., Perkins, Timothy N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910358/
https://www.ncbi.nlm.nih.gov/pubmed/36776857
http://dx.doi.org/10.3389/fimmu.2023.1039997