Computational design of CRISPR guide RNAs to enable strain-specific control of microbial consortia

Microbes naturally coexist in complex, multistrain communities. However, extracting individual microbes from and specifically manipulating the composition of these consortia remain challenging. The sequence-specific nature of CRISPR guide RNAs can be leveraged to accurately differentiate microorgani...

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Detalles Bibliográficos
Autores principales: Rottinghaus, Austin G., Vo, Steven, Moon, Tae Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910470/
https://www.ncbi.nlm.nih.gov/pubmed/36574681
http://dx.doi.org/10.1073/pnas.2213154120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910470/
https://www.ncbi.nlm.nih.gov/pubmed/36574681
http://dx.doi.org/10.1073/pnas.2213154120

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