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Mechanism of PKCε regulation of cardiac GIRK channel gating

G-protein-gated inwardly rectifying potassium (GIRK) channel activity is regulated by the membrane phospholipid, phosphatidylinositol-4,5-bisphosphate (PI 4,5P(2)). Constitutive activity of cardiac GIRK channels in atrial myocytes, that is implicated in atrial fibrillation (AF), is mediated via a pr...

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Detalles Bibliográficos
Autores principales:	Gada, Kirin D., Chang, Mengmeng, Chandrashekar, Aishwarya, Plant, Leigh D., Noujaim, Sami F., Logothetis, Diomedes E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910474/ https://www.ncbi.nlm.nih.gov/pubmed/36584301 http://dx.doi.org/10.1073/pnas.2212325120

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