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Piezo mechanosensory channels regulate centrosome integrity and mitotic entry

Piezo1 and 2 are evolutionarily conserved mechanosensory cation channels known to function on the cell surface by responding to external pressure and transducing a mechanically activated Ca(2+) current. Here we show that both Piezo1 and 2 also exhibit concentrated intracellular localization at centr...

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Detalles Bibliográficos
Autores principales: David, Liron, Martinez, Laurel, Xi, Qiongchao, Kooshesh, Kameron A., Zhang, Ying, Shah, Jagesh V., Maas, Richard L., Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910506/
https://www.ncbi.nlm.nih.gov/pubmed/36574677
http://dx.doi.org/10.1073/pnas.2213846120