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Bone marrow-derived IGF-1 orchestrates maintenance and regeneration of the adult skeleton
Insulin-like growth factor I (IGF-1) is a key regulator of tissue growth and development in response to growth hormone stimulation. In the skeletal system, IGF-1 derived from osteoblasts and chondrocytes are essential for normal bone development; however, whether bone marrow (BM)-resident cells prov...
Autores principales: | Wang, Jianfang, Zhu, Qiaoling, Cao, Dandan, Peng, Qiqi, Zhang, Xiaoying, Li, Chong, Zhang, Chen, Zhou, Bo O., Yue, Rui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910602/ https://www.ncbi.nlm.nih.gov/pubmed/36577075 http://dx.doi.org/10.1073/pnas.2203779120 |
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