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Do proton pump inhibitors alter the response to immune checkpoint inhibitors in cancer patients? A meta-analysis

INTRODUCTION: Gut microbiota can significantly affect the effectiveness of immune checkpoint inhibitors (ICIs) in cancer patients. Recently, antibiotics were shown to decrease survival rate of patients treated by ICIs. Proton pump inhibitors (PPIs) can indeed modulate microbiota’s diversity, therefo...

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Detalles Bibliográficos
Autores principales: Lopes, Sébastien, Pabst, Lucile, Dory, Anne, Klotz, Marion, Gourieux, Bénédicte, Michel, Bruno, Mascaux, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910608/
https://www.ncbi.nlm.nih.gov/pubmed/36776847
http://dx.doi.org/10.3389/fimmu.2023.1070076