Cargando…
Atf7ip and Setdb1 interaction orchestrates the hematopoietic stem and progenitor cell state with diverse lineage differentiation
Hematopoietic stem and progenitor cells (HSPCs) are a heterogeneous group of cells with expansion, differentiation, and repopulation capacities. How HSPCs orchestrate the stemness state with diverse lineage differentiation at steady condition or acute stress remains largely unknown. Here, we show th...
Autores principales: | Wu, Jiaxin, Li, Juan, Chen, Kang, Liu, Guolong, Zhou, Yating, Chen, Wenqi, Zhu, Xiangzhan, Ni, Terri T., Zhang, Bianhong, Jin, Daqing, Li, Dali, Kang, Lan, Wu, Yuxuan, Zhu, Ping, Xie, Peng, Zhong, Tao P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910619/ https://www.ncbi.nlm.nih.gov/pubmed/36577070 http://dx.doi.org/10.1073/pnas.2209062120 |
Ejemplares similares
-
Targeting the Atf7ip–Setdb1 Complex Augments Antitumor Immunity by Boosting Tumor Immunogenicity
por: Hu, Hai, et al.
Publicado: (2021) -
The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation
por: Minkovsky, Alissa, et al.
Publicado: (2014) -
ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex
por: Timms, Richard T., et al.
Publicado: (2016) -
Methyltransferase Setdb1 Promotes Osteoblast Proliferation by Epigenetically Silencing Macrod2 with the Assistance of Atf7ip
por: Zhang, Lijun, et al.
Publicado: (2022) -
The fibronectin type-III (FNIII) domain of ATF7IP contributes to efficient transcriptional silencing mediated by the SETDB1 complex
por: Tsusaka, Takeshi, et al.
Publicado: (2020)