Gain-of-function mutations in Trim71 linked to congenital hydrocephalus

The genetic basis of congenital hydrocephalus is only partially understood. A new study in PLOS Biology reports a potential gain-of-function pathological mechanism of congenital hydrocephalus in mouse embryonic stem cells that involves Wnt–β-catenin signaling pathway regulation.

Detalles Bibliográficos
Autores principales: Chen, Yingying, Yang, Xianfa, Jing, Naihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910648/
https://www.ncbi.nlm.nih.gov/pubmed/36757939
http://dx.doi.org/10.1371/journal.pbio.3001993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910648/
https://www.ncbi.nlm.nih.gov/pubmed/36757939
http://dx.doi.org/10.1371/journal.pbio.3001993

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