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Upregulation of programmed death ligand-1 in tumor-associated macrophages affects chemotherapeutic response in ovarian cancer cells

To better understand the mechanism of chemoresistance in ovarian cancer cells, we aimed to investigate the influence of macrophages on the tumor cell response to carboplatin and identify the genes associated with chemoresistance. We mimicked the tumor microenvironment (TME) using a co-culture techni...

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Detalles Bibliográficos
Autores principales: Jang, Yong Soo, Kim, Tae Wan, Ryu, Jae Sung, Kong, Hye Jeong, Jang, Si Hyeong, Nam, Gye Hyun, Kim, Jae Hoon, Jeon, Seob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910707/
https://www.ncbi.nlm.nih.gov/pubmed/36757936
http://dx.doi.org/10.1371/journal.pone.0277285