Detection of BRAF mutations in malignant melanoma and colorectal cancer by SensiScreen(®) FFPE BRAF qPCR assay

Mutations in BRAF exon 15 lead to conformational changes in its activation loops, resulting in constitutively active BRAF proteins which are implicated in the development of several human cancer types. Different BRAF inhibitors have been developed and introduced in clinical practice. Identification...

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Detalles Bibliográficos
Autores principales: Sørensen, Anna Lahn, Guldmann-Christensen, Mariann, Børgesen, Michael, Petersen, Rasmus Koefoed, Flugt, Katharina, Duelund, Julie Mejer Holmgaard, Kyneb, Majbritt Hauge, Lorenzen, Jan, Pipó-Ollé, Emma, Epistolio, Samantha, Riva, Alice, Dazio, Giulia, Merlo, Elisabetta, Meyer, Tine, Christensen, Ulf Bech, Frattini, Milo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910728/
https://www.ncbi.nlm.nih.gov/pubmed/36758042
http://dx.doi.org/10.1371/journal.pone.0281558

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