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The development of the national tuberculosis research priority in Indonesia: A comprehensive mixed-method approach

Ranked second in global tuberculosis (TB) incidence, Indonesia has developed a National Strategy for TB Prevention and Control 2020–2024 to accelerate the TB elimination program. Research and innovation are key pillars to support the program and need to be prioritised. This study aimed to develop up...

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Autores principales: Lestari, Trisasi, Fuady, Ahmad, Yani, Finny Fitry, Putra, I Wayan Gede Artawan Eka, Pradipta, Ivan Surya, Chaidir, Lidya, Handayani, Diah, Fitriangga, Agus, Loprang, Maria Regina, Pambudi, Imran, Ruslami, Rovina, Probandari, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910756/
https://www.ncbi.nlm.nih.gov/pubmed/36758064
http://dx.doi.org/10.1371/journal.pone.0281591
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author Lestari, Trisasi
Fuady, Ahmad
Yani, Finny Fitry
Putra, I Wayan Gede Artawan Eka
Pradipta, Ivan Surya
Chaidir, Lidya
Handayani, Diah
Fitriangga, Agus
Loprang, Maria Regina
Pambudi, Imran
Ruslami, Rovina
Probandari, Ari
author_facet Lestari, Trisasi
Fuady, Ahmad
Yani, Finny Fitry
Putra, I Wayan Gede Artawan Eka
Pradipta, Ivan Surya
Chaidir, Lidya
Handayani, Diah
Fitriangga, Agus
Loprang, Maria Regina
Pambudi, Imran
Ruslami, Rovina
Probandari, Ari
author_sort Lestari, Trisasi
collection PubMed
description Ranked second in global tuberculosis (TB) incidence, Indonesia has developed a National Strategy for TB Prevention and Control 2020–2024 to accelerate the TB elimination program. Research and innovation are key pillars to support the program and need to be prioritised. This study aimed to develop updated national TB research priorities in Indonesia. This study was a mixed-methods study consisting of an open survey, a published literature survey, and Delphi survey. The open survey invited all related TB stakeholders to answer (a) the main barriers of the TB program and (b) the need for studies to support TB elimination. The published literature survey retrieved scientific articles published in national and international journals between 2015 and 2020 to identify gaps between published research and the current national strategy for TB control. The online survey and literature survey informed a panel of TB experts in a two-phase Delphi Survey to select the top 10 priority research topics. We identified 322 articles and analysed 1143 open survey responses. Through two-phases Delphi surveys, top ten research categories were listed: early TB detection; diagnosis and treatment of DR-TB; contact investigation; case detection and treatment of child TB; TB preventive therapy; government policy; laboratory for drug-sensitive- and drug-resistant-TB diagnosis; treatment adherence; diagnostic tool development; and community empowerment. This study also found the gap between stakeholders’ interests and the importance of translating research into policy and practice. TB research priorities have been identified through the involvement of various stakeholders. The combination of an online survey, a published literature survey, and a Delphi survey was a rigorous methodology and was fit to build a systematic consensus about the priority of TB research.
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spelling pubmed-99107562023-02-10 The development of the national tuberculosis research priority in Indonesia: A comprehensive mixed-method approach Lestari, Trisasi Fuady, Ahmad Yani, Finny Fitry Putra, I Wayan Gede Artawan Eka Pradipta, Ivan Surya Chaidir, Lidya Handayani, Diah Fitriangga, Agus Loprang, Maria Regina Pambudi, Imran Ruslami, Rovina Probandari, Ari PLoS One Research Article Ranked second in global tuberculosis (TB) incidence, Indonesia has developed a National Strategy for TB Prevention and Control 2020–2024 to accelerate the TB elimination program. Research and innovation are key pillars to support the program and need to be prioritised. This study aimed to develop updated national TB research priorities in Indonesia. This study was a mixed-methods study consisting of an open survey, a published literature survey, and Delphi survey. The open survey invited all related TB stakeholders to answer (a) the main barriers of the TB program and (b) the need for studies to support TB elimination. The published literature survey retrieved scientific articles published in national and international journals between 2015 and 2020 to identify gaps between published research and the current national strategy for TB control. The online survey and literature survey informed a panel of TB experts in a two-phase Delphi Survey to select the top 10 priority research topics. We identified 322 articles and analysed 1143 open survey responses. Through two-phases Delphi surveys, top ten research categories were listed: early TB detection; diagnosis and treatment of DR-TB; contact investigation; case detection and treatment of child TB; TB preventive therapy; government policy; laboratory for drug-sensitive- and drug-resistant-TB diagnosis; treatment adherence; diagnostic tool development; and community empowerment. This study also found the gap between stakeholders’ interests and the importance of translating research into policy and practice. TB research priorities have been identified through the involvement of various stakeholders. The combination of an online survey, a published literature survey, and a Delphi survey was a rigorous methodology and was fit to build a systematic consensus about the priority of TB research. Public Library of Science 2023-02-09 /pmc/articles/PMC9910756/ /pubmed/36758064 http://dx.doi.org/10.1371/journal.pone.0281591 Text en © 2023 Lestari et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Lestari, Trisasi
Fuady, Ahmad
Yani, Finny Fitry
Putra, I Wayan Gede Artawan Eka
Pradipta, Ivan Surya
Chaidir, Lidya
Handayani, Diah
Fitriangga, Agus
Loprang, Maria Regina
Pambudi, Imran
Ruslami, Rovina
Probandari, Ari
The development of the national tuberculosis research priority in Indonesia: A comprehensive mixed-method approach
title The development of the national tuberculosis research priority in Indonesia: A comprehensive mixed-method approach
title_full The development of the national tuberculosis research priority in Indonesia: A comprehensive mixed-method approach
title_fullStr The development of the national tuberculosis research priority in Indonesia: A comprehensive mixed-method approach
title_full_unstemmed The development of the national tuberculosis research priority in Indonesia: A comprehensive mixed-method approach
title_short The development of the national tuberculosis research priority in Indonesia: A comprehensive mixed-method approach
title_sort development of the national tuberculosis research priority in indonesia: a comprehensive mixed-method approach
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910756/
https://www.ncbi.nlm.nih.gov/pubmed/36758064
http://dx.doi.org/10.1371/journal.pone.0281591
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