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Tissue specific LRRK2 interactomes reveal a distinct striatal functional unit

Mutations in LRRK2 are the most common genetic cause of Parkinson’s disease. Despite substantial research efforts, the physiological and pathological role of this multidomain protein remains poorly defined. In this study, we used a systematic approach to construct the general protein-protein interac...

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Detalles Bibliográficos
Autores principales:	Zhao, Yibo, Vavouraki, Nikoleta, Lovering, Ruth C., Escott-Price, Valentina, Harvey, Kirsten, Lewis, Patrick A., Manzoni, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910798/ https://www.ncbi.nlm.nih.gov/pubmed/36716346 http://dx.doi.org/10.1371/journal.pcbi.1010847

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