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The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
The severe acute respiratory syndrome associated coronavirus 2 (SARS-CoV-2) and SARS-CoV-1 accessory protein Orf3a colocalizes with markers of the plasma membrane, endocytic pathway, and Golgi apparatus. Some reports have led to annotation of both Orf3a proteins as viroporins. Here, we show that nei...
Autores principales: | Miller, Alexandria N, Houlihan, Patrick R, Matamala, Ella, Cabezas-Bratesco, Deny, Lee, Gi Young, Cristofori-Armstrong, Ben, Dilan, Tanya L, Sanchez-Martinez, Silvia, Matthies, Doreen, Yan, Rui, Yu, Zhiheng, Ren, Dejian, Brauchi, Sebastian E, Clapham, David E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910834/ https://www.ncbi.nlm.nih.gov/pubmed/36695574 http://dx.doi.org/10.7554/eLife.84477 |
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