Idiopathic Orbital Inflammation Treated With Rituximab Monotherapy

Idiopathic orbital inflammation is a benign condition that affects the orbit and the extra-orbital structures. It presents as ocular pain, peri-orbital swelling, proptosis, and restricted ocular movements. This condition is diagnosed based on clinical features that are then confirmed by radiological...

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Detalles Bibliográficos
Autores principales: Bawazeer, Amani, Rahali, Wejdan, Alsharif, Alhanouf, Alshehri, Malak, Maksood, Lama, Babkier, Ahad, Hommadi, Walaa, Othman, Basant, Omair, Mohammed A, Hafiz, Waleed A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Ophthalmology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911136/
https://www.ncbi.nlm.nih.gov/pubmed/36788832
http://dx.doi.org/10.7759/cureus.33614
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author Bawazeer, Amani
Rahali, Wejdan
Alsharif, Alhanouf
Alshehri, Malak
Maksood, Lama
Babkier, Ahad
Hommadi, Walaa
Othman, Basant
Omair, Mohammed A
Hafiz, Waleed A
author_facet Bawazeer, Amani
Rahali, Wejdan
Alsharif, Alhanouf
Alshehri, Malak
Maksood, Lama
Babkier, Ahad
Hommadi, Walaa
Othman, Basant
Omair, Mohammed A
Hafiz, Waleed A
author_sort Bawazeer, Amani
collection PubMed
description Idiopathic orbital inflammation is a benign condition that affects the orbit and the extra-orbital structures. It presents as ocular pain, peri-orbital swelling, proptosis, and restricted ocular movements. This condition is diagnosed based on clinical features that are then confirmed by radiological and histopathological findings. Corticosteroids are the initial therapy of choice. Disease-modifying antirheumatic drugs are added in steroid non-responsive patients. Rituximab is now becoming increasingly used as a third-line therapy for this disease. We report a case of idiopathic orbital inflammation treated with rituximab monotherapy without the use of corticosteroids or disease-modifying antirheumatic drugs.
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spelling pubmed-99111362023-02-13 Idiopathic Orbital Inflammation Treated With Rituximab Monotherapy Bawazeer, Amani Rahali, Wejdan Alsharif, Alhanouf Alshehri, Malak Maksood, Lama Babkier, Ahad Hommadi, Walaa Othman, Basant Omair, Mohammed A Hafiz, Waleed A Cureus Ophthalmology Idiopathic orbital inflammation is a benign condition that affects the orbit and the extra-orbital structures. It presents as ocular pain, peri-orbital swelling, proptosis, and restricted ocular movements. This condition is diagnosed based on clinical features that are then confirmed by radiological and histopathological findings. Corticosteroids are the initial therapy of choice. Disease-modifying antirheumatic drugs are added in steroid non-responsive patients. Rituximab is now becoming increasingly used as a third-line therapy for this disease. We report a case of idiopathic orbital inflammation treated with rituximab monotherapy without the use of corticosteroids or disease-modifying antirheumatic drugs. Cureus 2023-01-10 /pmc/articles/PMC9911136/ /pubmed/36788832 http://dx.doi.org/10.7759/cureus.33614 Text en Copyright © 2023, Bawazeer et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Ophthalmology
Bawazeer, Amani
Rahali, Wejdan
Alsharif, Alhanouf
Alshehri, Malak
Maksood, Lama
Babkier, Ahad
Hommadi, Walaa
Othman, Basant
Omair, Mohammed A
Hafiz, Waleed A
Idiopathic Orbital Inflammation Treated With Rituximab Monotherapy
title Idiopathic Orbital Inflammation Treated With Rituximab Monotherapy
title_full Idiopathic Orbital Inflammation Treated With Rituximab Monotherapy
title_fullStr Idiopathic Orbital Inflammation Treated With Rituximab Monotherapy
title_full_unstemmed Idiopathic Orbital Inflammation Treated With Rituximab Monotherapy
title_short Idiopathic Orbital Inflammation Treated With Rituximab Monotherapy
title_sort idiopathic orbital inflammation treated with rituximab monotherapy
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911136/
https://www.ncbi.nlm.nih.gov/pubmed/36788832
http://dx.doi.org/10.7759/cureus.33614
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