Methodological approaches to optimize multiplex oral fluid SARS-CoV-2 IgG assay performance and correlation with serologic and neutralizing antibody responses

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BACKGROUND: Oral fluid (hereafter, saliva) is a non-invasive and attractive alternative to blood for SARS-CoV-2 IgG testing; however, the heterogeneity of saliva as a matrix poses challenges for immunoassay performance. OBJECTIVES: To optimize performance of a magnetic microparticle-based multiplex...

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Detalles Bibliográficos
Autores principales: Pisanic, Nora, Antar, Annukka A.R., Kruczynski, Kate L., Gregory Rivera, Magdielis, Dhakal, Santosh, Spicer, Kristoffer, Randad, Pranay R., Pekosz, Andrew, Klein, Sabra L., Betenbaugh, Michael J., Detrick, Barbara, Clarke, William, Thomas, David L., Manabe, Yukari C., Heaney, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911157/
https://www.ncbi.nlm.nih.gov/pubmed/36773929
http://dx.doi.org/10.1016/j.jim.2023.113440
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