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Simvastatin Reduces NETosis to Attenuate Severe Asthma by Inhibiting PAD4 Expression

OBJECTIVE: Patients with severe asthma respond poorly to corticosteroids, and their care accounts for more than 60% of the total costs attributed to asthma. Neutrophils form neutrophil extracellular traps (NETs), which play a crucial role in severe asthma. Statins have shown anti-inflammatory effect...

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Detalles Bibliográficos
Autores principales:	Chen, Yun-Rong, Xiang, Xu-Dong, Sun, Fei, Xiao, Bo-Wen, Yan, Mu-Yun, Peng, Biao, Liu, Da
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911252/ https://www.ncbi.nlm.nih.gov/pubmed/36778209 http://dx.doi.org/10.1155/2023/1493684

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